Is your primary goal (running from a USB) or just a fast installation ?
Multisim is a premium, paid product. Using an unauthorized portable version often violates the End User License Agreement (EULA). The Safe Alternative: Multisim Live
and extensive component library. While the official version from NI (National Instruments)
Multisim 14.1 remains one of the most powerful tools for circuit design. A portable version offers unmatched convenience for engineers who are always on the move. However, always prioritize the security of your workstation. If you choose to use a portable version, ensure it is from a trusted source and backed by a robust antivirus.