If you attempt to boot a standard Ghost ISO on a strictly UEFI machine (with CSM/Legacy mode disabled), it will fail to boot.
Have an old Ghost image you need to restore? You can use a legacy machine or virtualize an old BIOS environment. But for any new system: leave Ghost buried. norton ghost iso uefi link
Since Norton Ghost is discontinued and lacks native UEFI optimization, most IT professionals and advanced users have switched to modern, actively maintained alternatives that fully support UEFI, GPT, and modern hardware: If you attempt to boot a standard Ghost